We are pleased to announce our participation in the 4^th Circular & Self-Amplifying RNA Therapeutics Summit, taking place from May 28^th (Wednesday) to 29^th (Thursday), 2025, at The Colonnade Hotel in Boston, MA USA. We will also deliver an insightful poster presentation. We warmly invite you to visit our presentation to explore our latest advancements and innovative solutions in RNA-based technologies.

【Event details】
Official website: Circular & Self-Amplifying RNA Therapeutics | Home

【Poster presentation】
Strategies to establish effective and safe mRNA-based therapeutics:
Dr. Yanwen Feng

【Abstract】
ARCALIS, Inc. is a CDMO specializing in mRNA-based therapeutics and vaccines, offering services from sequence design to commercial manufacturing. In partnership with Axcelead Drug discovery Partners, Inc., the group company of Axcelead, Inc., ARCALIS also supports preclinical drug development, including animal studies for IND applications. Since 2024, ARCALIS has commercially produced self-amplifying mRNA (saRNA) for COVID-19 vaccines. This presentation outlines strategies for developing safe and effective mRNA therapeutics, focusing on sequence optimization, dsRNA reduction, mRNA-LNP formulation, and saRNA manufacturing.